Consider the compound . Which of the following would be considered a nucleophilic site?
A
The hydrogen atoms in the methyl group
B
The carbon atom in the methyl group
C
The hydrogen atom bonded to oxygen
D
The oxygen atom in
0 댓글
검증된 단계별 안내
1
Identify the structure of the compound CH\_3OH (methanol), which consists of a methyl group (CH\_3) attached to a hydroxyl group (OH).
Recall that a nucleophile is an electron-rich species that donates a pair of electrons to an electrophile during a chemical reaction.
Examine each site: hydrogen atoms in the methyl group are bonded to carbon and generally not electron-rich; the carbon atom in the methyl group is bonded to hydrogens and oxygen but is not particularly electron-rich; the hydrogen atom bonded to oxygen is slightly positive due to the electronegativity of oxygen, so it is not nucleophilic.
Focus on the oxygen atom in the hydroxyl group, which has lone pairs of electrons and a partial negative charge, making it electron-rich and capable of donating electrons.
Conclude that the oxygen atom in CH\_3OH is the nucleophilic site because it can donate a lone pair of electrons to an electrophile.