Provide the major product for the following reaction
A
B
C
D
2 댓글
검증된 단계별 안내
1
The reaction begins with the deprotonation of the alpha carbon of the diethyl malonate by sodium ethoxide (NaOEt) in ethanol (EtOH), forming an enolate ion.
The enolate ion then acts as a nucleophile and attacks the electrophilic carbon in 1-bromopropane (CH3CH2CH2Br), resulting in an alkylation reaction. This step adds a propyl group to the alpha carbon of the diethyl malonate.
Next, the diethyl malonate undergoes hydrolysis in the presence of sodium hydroxide (NaOH) and water (H2O), converting the ester groups into carboxylic acids.
The resulting dicarboxylic acid is then subjected to decarboxylation under acidic conditions (H3O+) and heat, which removes one of the carboxyl groups as carbon dioxide (CO2), leaving behind a mono-carboxylic acid.
The final product is a carboxylic acid with a propyl group attached to the alpha carbon, which is the major product of this reaction sequence.