A Michael acceptor undergoes conjugate addition, making it carcinogenic. Glutathione counteracts this by reacting with the carcinogen as shown below. Draw the expected inactivated carcinogen that forms between the carcinogen and glutathione. Represent the rest of glutathione as R.

Predict the missing products in the following sequence.

The following reaction occurs in acidic conditions, but a mechanism can be proposed for when it occurs in basic conditions.

Is the proposed mechanism for the basic condition shown below possible? (Note: The most acidic proton is shown.)

Draw the structures of the major products expected from the reaction sequence below.

Draw the mechanism for the base-catalyzed aldol condensation of cyclopentanone. Based on the mechanism, state the direction the equilibrium favors.

How can the following compound be prepared beginning with an aldol addition?

Write the complete mechanism of the base-catalyzed condensation followed by dehydration between formaldehyde and butanal.

Determine the possible major product of base-catalyzed aldol condensation followed by dehydration between p-nitrobenzophenone and acetaldehyde.

Give the major product of the reaction below.