How might hemoglobin's affinity for oxygen change in response to high carbon dioxide levels?

• A. Hemoglobin's affinity for carbon dioxide decreases.
• B. Hemoglobin's affinity for oxygen increases, making it harder to release oxygen.
• C. Hemoglobin's affinity remains unchanged regardless of carbon dioxide levels.
• D. Hemoglobin's affinity for oxygen decreases, facilitating oxygen release to tissues.

Answer: (D)