Mineral bone disease is a common problem in patients with chronic kidney disease. Why are the bones affected in people with kidney disease:

• A. It is involved in the regulation of calcium and phosphate homeostasis
• B. The kidneys are responsible for the regulation of osteoblast activity
• C. The kidneys convert cholecalciferol into calcidiol which is then converted into its active form calcitriol the active form of vit. D
• D. A and B only
• E. All of the above

Answer: (D)