Following the binding of antibodies to a pathogen, what is the sequence of events leading to the activation of C3 convertase?

• A. C5 activation -> MAC formation -> C3 convertase formation
• B. C3a and C5a release -> Inflammation -> C3 convertase formation
• C. C1 activation -> C4 and C2 cleavage -> C3 convertase formation
• D. MAC formation -> Pathogen lysis -> C3 convertase formation

Answer: (C)