Which of the following structural features distinguishes prokaryotic chromosomal organization from eukaryotic chromosomal organization?

• A. Prokaryotic chromosomes are found within a nucleus, while eukaryotic chromosomes are not.
• B. Prokaryotic chromosomes contain introns, while eukaryotic chromosomes do not.
• C. Prokaryotic chromosomes are linear, while eukaryotic chromosomes are circular.
• D. Prokaryotic chromosomes are typically single and circular, while eukaryotic chromosomes are multiple and linear.

Answer: (D)