What are the three basic parts of a generalized cell?
Plasma membrane, cytoplasm, and nucleus.
What is the primary function of the plasma membrane?
Acts as a barrier separating intracellular fluid from extracellular fluid and controls what enters and leaves the cell.
What is the composition of the plasma membrane lipid bilayer?
75% phospholipids with hydrophilic heads and hydrophobic tails, 5% glycolipids, and 20% cholesterol.
What are the two types of membrane proteins and their functions?
Integral proteins are transmembrane and function as transport proteins; peripheral proteins are loosely attached and function as enzymes and motor proteins.
What are the two main types of membrane transport?
Passive processes (no energy required) and active processes (energy required).
What is diffusion and what drives it?
Movement of molecules down their concentration gradient from high to low concentration without energy.
What is facilitated diffusion?
Passive transport of hydrophobic molecules down their concentration gradient via carrier proteins or channel proteins.
What distinguishes active membrane transport from passive transport?
Active transport requires ATP to move solutes against their concentration gradient using carrier proteins.
What is the sodium-potassium pump and its role?
An antiporter that pumps 3 Na+ out and 2 K+ into the cell against their gradients, maintaining electrochemical balance.
What is vesicular transport?
Transport of large particles or fluids across the membrane in vesicles, requiring ATP.
Name the types of vesicular transport.
Endocytosis, exocytosis, transcytosis, and vesicular trafficking.
What is phagocytosis?
Type of endocytosis where the cell engulfs large particles like bacteria or debris ('cell eating').
What is pinocytosis?
Type of endocytosis where the cell ingests extracellular fluid and dissolved solutes ('cell drinking').
What is exocytosis?
Process where materials enclosed in secretory vesicles are ejected from the cell.
What is resting membrane potential (RMP)?
Electrical potential across the plasma membrane due to ionic imbalances, typically -50 to -100 mV.
What maintains the resting membrane potential?
Diffusion of K+ out of the cell balanced by electrical attraction to the negative interior.
What are the main components of the cytoplasm?
Cytosol (gel-like fluid), inclusions (insoluble molecules), and organelles.
What is the function of mitochondria?
Produce most of the cell's ATP via aerobic cellular respiration.
What are the two types of endoplasmic reticulum and their functions?
Rough ER synthesizes proteins; Smooth ER is involved in lipid metabolism, detoxification, and calcium storage.
What is the role of the Golgi apparatus?
Modifies, concentrates, and packages proteins and lipids from the rough ER for transport.
What are microvilli?
Fingerlike projections from the cell surface that increase surface area for absorption.
What is the nucleus and its significance?
Control center of the cell containing DNA; most cells have one nucleus.