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Anatomy & Physiology: Cell Structure and Membrane Transport

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  • What are the three basic parts of a generalized cell?

    Plasma membrane, cytoplasm, and nucleus.
  • What is the primary function of the plasma membrane?

    Acts as a barrier separating intracellular fluid from extracellular fluid and controls what enters and leaves the cell.
  • What is the composition of the plasma membrane lipid bilayer?

    75% phospholipids with hydrophilic heads and hydrophobic tails, 5% glycolipids, and 20% cholesterol.
  • What are the two types of membrane proteins and their functions?

    Integral proteins are transmembrane and function as transport proteins; peripheral proteins are loosely attached and function as enzymes and motor proteins.
  • What are the two main types of membrane transport?

    Passive processes (no energy required) and active processes (energy required).
  • What is diffusion and what drives it?

    Movement of molecules down their concentration gradient from high to low concentration without energy.
  • What is facilitated diffusion?

    Passive transport of hydrophobic molecules down their concentration gradient via carrier proteins or channel proteins.
  • What distinguishes active membrane transport from passive transport?

    Active transport requires ATP to move solutes against their concentration gradient using carrier proteins.
  • What is the sodium-potassium pump and its role?

    An antiporter that pumps 3 Na+ out and 2 K+ into the cell against their gradients, maintaining electrochemical balance.
  • What is vesicular transport?

    Transport of large particles or fluids across the membrane in vesicles, requiring ATP.
  • Name the types of vesicular transport.

    Endocytosis, exocytosis, transcytosis, and vesicular trafficking.
  • What is phagocytosis?

    Type of endocytosis where the cell engulfs large particles like bacteria or debris ('cell eating').
  • What is pinocytosis?

    Type of endocytosis where the cell ingests extracellular fluid and dissolved solutes ('cell drinking').
  • What is exocytosis?

    Process where materials enclosed in secretory vesicles are ejected from the cell.
  • What is resting membrane potential (RMP)?

    Electrical potential across the plasma membrane due to ionic imbalances, typically -50 to -100 mV.
  • What maintains the resting membrane potential?

    Diffusion of K+ out of the cell balanced by electrical attraction to the negative interior.
  • What are the main components of the cytoplasm?

    Cytosol (gel-like fluid), inclusions (insoluble molecules), and organelles.
  • What is the function of mitochondria?

    Produce most of the cell's ATP via aerobic cellular respiration.
  • What are the two types of endoplasmic reticulum and their functions?

    Rough ER synthesizes proteins; Smooth ER is involved in lipid metabolism, detoxification, and calcium storage.
  • What is the role of the Golgi apparatus?

    Modifies, concentrates, and packages proteins and lipids from the rough ER for transport.
  • What are microvilli?

    Fingerlike projections from the cell surface that increase surface area for absorption.
  • What is the nucleus and its significance?

    Control center of the cell containing DNA; most cells have one nucleus.