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Anatomy & Physiology: Cells and Membrane Transport

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  • What is the cell theory?

    A cell is the structural and functional unit of life. The organism's function depends on the activities of all its cells. Cells arise only from preexisting cells.

  • What are the three basic parts of a generalized human cell?

    Plasma membrane (flexible outer boundary), cytoplasm (intracellular fluid with organelles), and nucleus (DNA-containing control center).

  • What are extracellular materials?

    Substances outside cells including extracellular fluids (interstitial fluid, blood plasma, cerebrospinal fluid), cellular secretions (saliva, mucus), and extracellular matrix (glue holding cells together).

  • What is the plasma membrane and its main function?

    The plasma membrane is a selectively permeable lipid bilayer that separates intracellular fluid from extracellular fluid and controls what enters and leaves the cell.

  • Describe the fluid mosaic model of the plasma membrane.

    The membrane consists of a lipid bilayer with floating specialized proteins that create a constantly changing mosaic pattern.

  • What are the main components of the membrane lipids?

    75% phospholipids (polar heads hydrophilic, nonpolar tails hydrophobic), 5% glycolipids, and 20% cholesterol which stabilizes the membrane.

  • What are integral and peripheral membrane proteins?

    Integral proteins span the membrane and function as transporters, enzymes, or receptors. Peripheral proteins attach loosely and support membrane structure and cell connections.

  • What is the glycocalyx and its function?

    A sugar coating on the cell surface made of carbohydrates attached to lipids and proteins. It acts as a biological marker for cell recognition and immune system identification.

  • Name the three types of cell junctions and their functions.

    Tight junctions prevent fluid leakage, desmosomes provide mechanical strength, and gap junctions allow communication via small molecule passage.

  • What is passive transport across the plasma membrane?

    Movement of substances down their concentration gradient without energy input, including simple diffusion, facilitated diffusion, and osmosis.

  • What factors influence the speed of diffusion?

    Concentration gradient, molecular size (smaller diffuses faster), and temperature (higher temperature increases diffusion speed).

  • What types of molecules can pass by simple diffusion?

    Nonpolar, lipid-soluble substances like oxygen, carbon dioxide, steroid hormones, and small amounts of water.

  • How does facilitated diffusion differ from simple diffusion?

    Facilitated diffusion requires carrier proteins or channels to transport larger or polar molecules like glucose and ions down their concentration gradient.

  • What are the two types of facilitated diffusion?

    Carrier-mediated uses protein carriers that change shape to move molecules; channel-mediated uses aqueous channels for ions or water.

  • What is osmosis?

    Movement of solvent (usually water) across a selectively permeable membrane from an area of low solute concentration to high solute concentration.

  • Define osmolarity and its effect on water concentration.

    Osmolarity measures total solute particles in solution. Higher solute concentration means lower water concentration, driving water movement by osmosis.

  • What is tonicity and its types?

    Tonicity is a solution's ability to change cell shape by altering water volume. Isotonic (no change), hypertonic (cell shrinks), hypotonic (cell swells).

  • What happens to animal cells in hypotonic solutions?

    Water enters the cell causing it to swell and potentially burst, a process called lysis.

  • What is the role of hydrostatic and osmotic pressure in osmosis?

    Hydrostatic pressure pushes water out of the cell; osmotic pressure pulls water into the cell. Equilibrium occurs when these pressures balance.

  • How do plant cells prevent bursting in hypotonic solutions?

    Plant cell walls limit hydrostatic pressure, preventing excessive water intake and cell bursting.