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Anatomy & Physiology: Central Nervous System and Brain Functions

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  • Central Nervous System (CNS)

    The CNS consists of the brain and spinal cord, responsible for processing and integrating information.

  • Major brain regions

    Cerebral hemispheres, diencephalon, brain stem, and cerebellum, each with distinct functions like higher cognition, sensory relay, autonomic control, and coordination.

  • Cerebral hemispheres

    Responsible for higher brain functions such as thought, action, and sensory processing; composed of cortex, white matter, and basal nuclei.

  • Diencephalon components

    Includes the thalamus (sensory relay), hypothalamus (homeostasis and endocrine control), and epithalamus (sleep-wake regulation).

  • Brain stem functions

    Controls basic life functions like breathing, heartbeat, and blood pressure; includes midbrain, pons, and medulla oblongata.

  • Cerebellum role

    Coordinates voluntary movements, posture, balance, and speech; processes inputs from motor cortex and sensory pathways.

  • Cerebral cortex functional areas

    Divided into motor areas (voluntary movement), sensory areas (conscious sensation), and association areas (integration and cognition).

  • Motor homunculus

    Spatial representation of body parts in the primary motor cortex, showing disproportionate control for precise movements.

  • Basal nuclei (ganglia)

    Subcortical gray matter involved in movement control, cognition, and emotion; includes caudate nucleus, putamen, and globus pallidus.

  • Thalamus function

    Acts as a relay station for sensory and motor signals to the cerebral cortex, sorting and editing information.

  • Hypothalamus functions

    Main visceral control center regulating autonomic nervous system, body temperature, hunger, thirst, sleep cycles, and endocrine system.

  • Epithalamus and pineal gland

    Epithalamus contains the pineal gland, which secretes melatonin to regulate sleep-wake cycles.

  • Reticular activating system (RAS)

    Part of the reticular formation that maintains cerebral cortical alertness and filters sensory input.

  • Limbic system

    Network of brain structures involved in emotions, memory, and visceral responses, including the amygdala and hippocampus.

  • Memory types

    Includes declarative (facts), procedural (skills), motor, and emotional memory, processed and stored in different brain areas.

  • Stages of memory

    Short-term memory (STM) holds limited info temporarily; long-term memory (LTM) stores information indefinitely with consolidation.

  • Electroencephalogram (EEG) brain waves

    Alpha (relaxed), beta (alert), theta (children/early sleep), and delta (deep sleep) waves reflect brain electrical activity patterns.

  • Sleep stages

    Non-REM sleep includes stages N1-N3 with slow-wave sleep; REM sleep involves rapid eye movement and dreaming with muscle inhibition.

  • Blood-brain barrier (BBB)

    Protective barrier formed by tight junctions in brain capillaries, regulating substance passage to maintain neural environment stability.

  • Cerebrospinal fluid (CSF) functions

    Provides buoyancy, cushions the brain and spinal cord, removes waste, and maintains chemical stability.

  • Spinal cord structure

    Extends from foramen magnum to lumbar region; gray matter inside (butterfly-shaped), white matter outside; protected by meninges and CSF.

  • Ascending sensory pathways

    Carry sensory information to the brain via chains of first-, second-, and third-order neurons; include dorsal column-medial lemniscal and spinothalamic tracts.

  • Descending motor pathways

    Deliver motor commands from brain to spinal cord; include direct (pyramidal) and indirect pathways controlling voluntary and subconscious movements.

  • Decussation

    Most neural pathways cross from one side of the CNS to the other, causing contralateral control of body functions.

  • Flaccid vs. spastic paralysis

    Flaccid paralysis results from lower motor neuron damage causing muscle limpness; spastic paralysis results from upper motor neuron damage causing increased muscle tone.

  • Neural tube development

    The CNS develops from the neural tube, which forms primary brain vesicles that differentiate into major brain regions.

  • Common CNS disorders

    Include strokes (CVA), Alzheimer's disease, Parkinson's disease, Huntington's disease, and traumatic brain injuries.

  • Cerebral lateralization

    Specialization of each hemisphere; left hemisphere typically dominant for language and logic, right for visual-spatial and creativity.