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Anatomy & Physiology I Unit 1 Exam Review

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  • Ionic bond

    Electrons are transferred from one atom to another, creating oppositely charged ions that attract each other.

  • Covalent bond

    Electrons are shared between atoms to fill their valence shells; can be polar or nonpolar.

  • Polar covalent bond

    Unequal sharing of electrons causes partial charges on atoms, creating polarity.

  • Nonpolar covalent bond

    Equal sharing of electrons results in no partial charges and nonpolar molecules.

  • Hydrogen bond

    Weak attraction between a partially positive hydrogen and a electronegative atom like oxygen or nitrogen.

  • Na⁺/K⁺ ATPase pump

    Active transport protein that uses ATP hydrolysis to move Na⁺ out and K⁺ into the cell against their gradients.

  • Formation of cations and anions

    Atoms lose electrons to form cations (+) or gain electrons to form anions (−), changing their charge.

  • GPCR signaling pathway sequence

    Ligand → receptor → G protein → intracellular enzyme → second messenger → intracellular response.

  • Principle: Structure determines function

    The shape and organization of molecules and cells directly affect their physiological roles and functions.

  • Levels of biological organization

    Chemical → Cellular → Tissue → Organ → Organ System → Organism.

  • Membrane permeability to polar vs. nonpolar molecules

    Nonpolar molecules cross membranes more easily due to the hydrophobic lipid bilayer; polar molecules cross less readily.

  • Resting membrane potential main ion

    K⁺ concentration gradient and membrane permeability contribute most to the resting membrane potential.

  • ATP hydrolysis

    Breaking down ATP releases energy used to power active transport and other cellular processes.

  • Osmosis definition

    Passive movement of water across a selectively permeable membrane from low to high solute concentration; no ATP required.

  • Fluid mosaic model

    Plasma membrane is fluid due to phospholipid movement; proteins and cholesterol contribute to membrane structure and function.

  • Negative feedback

    Response reduces or reverses original stimulus to maintain homeostasis, moving variables toward set point.

  • Positive feedback

    Response amplifies original stimulus until a specific event terminates the loop.

  • Simple diffusion characteristics

    Movement of molecules down their concentration gradient without protein or ATP; typically small nonpolar molecules.

  • Facilitated diffusion through carriers

    Substrate binds carrier protein, which changes shape to transport molecule down its gradient; no ATP required; can saturate.

  • Isotonic solution

    Extracellular solute concentration equals intracellular; no net water movement; cell volume remains stable.

  • Buffer function

    Resists pH changes by neutralizing added H⁺ or OH⁻ ions, maintaining pH homeostasis within limits.

  • Hydrophilic substances

    Polar or charged molecules that interact well with water and dissolve easily.

  • Hydrophobic substances

    Nonpolar molecules that do not dissolve well in water but dissolve in lipids.

  • Membrane transport proteins types

    Channels allow passive flow; carriers bind and transport substrates; pumps use ATP for active transport.

  • Cholesterol role in plasma membrane

    Regulates membrane fluidity, stiffness, permeability, and stability.

  • Lipid bilayer permeability

    Nonpolar molecules cross easily; polar molecules face resistance due to hydrophobic interior.

  • pH determination

    pH depends on H⁺ concentration: increase in H⁺ lowers pH (acidic), decrease raises pH (basic).

  • Plasma membrane hydrophilic head

    Located on membrane surface; interacts with aqueous environments inside and outside the cell.

  • Tonicity definition

    Effect of extracellular solute concentration on cell volume and water movement.

  • Intracellular fluid

    Fluid inside cells, distinct from extracellular fluid outside cells.

  • Diffusion driving force

    Molecules move down concentration gradients due to random thermal motion without ATP.