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Anatomy & Physiology: Membrane Transport and Cell Environment

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  • What is passive transport?

    Passive transport is the movement of substances across a membrane without using ATP, often carrier mediated or by diffusion.

  • Define facilitated diffusion.

    Facilitated diffusion is carrier-mediated diffusion using membrane proteins to transport larger molecules and water-soluble ions without ATP.

  • What types of molecules does simple diffusion allow through the membrane?

    Simple diffusion allows small molecules, lipid-soluble substances, and dissolved gases to pass through the membrane.

  • What is osmosis?

    Osmosis is the diffusion of water from an area of high concentration to low concentration across a membrane.

  • List factors affecting facilitated diffusion.

    Factors include size of molecules, charge, and availability of channels.

  • What factors affect diffusion in general?

    Diffusion is affected by size of molecules, temperature, electrical forces, and the concentration gradient.

  • Describe the cytosol composition relevant to ion concentration.

    The cytosol has high potassium, low protein, and some glycogen.

  • Why do red blood cells have a limited lifespan?

    Red blood cells lack a nucleus, so they cannot synthesize proteins, limiting their lifespan.

  • What happens to cells in a hypotonic solution?

    Cells in a hypotonic solution gain water and may burst (hemolysis).

  • What happens to cells in a hypertonic solution?

    Cells in a hypertonic solution lose water and undergo crenation (shrink).

  • Define tonicity.

    Tonicity describes how a solution affects the size of a cell.

  • What is osmolarity?

    Osmolarity is the total concentration of dissolved particles in a solution.

  • What is carrier-mediated transport?

    Carrier-mediated transport involves carriers that bind specific molecules to move them across membranes.

  • What is saturation in carrier-mediated transport?

    Saturation occurs when carriers are full, limiting the rate of transport across the membrane.

  • How is carrier-mediated transport regulated?

    It is regulated by cofactors such as hormones.

  • What is cotransport?

    Cotransport moves two substances in the same direction across a membrane.

  • What is countertransport?

    Countertransport moves one substance in and another out of the cell simultaneously.

  • What is the typical isotonic concentration for red blood cells?

    0.9% concentration is isotonic where red blood cells do not change shape.

  • Give examples of hypotonic and hypertonic concentrations mentioned.

    0.1% is hypotonic; 10% is hypertonic relative to red blood cells.