The cell is the basic building block and the smallest unit of life in the body.
Name the main components of a cell.
A cell is comprised of the plasma membrane, cytoplasm, nucleus, and organelles such as ribosomes, mitochondria, and lysosomes.
What is the function of the plasma membrane?
The plasma membrane encloses cell contents and separates the intracellular fluid from the extracellular fluid.
Describe the phospholipid bilayer of the plasma membrane.
It consists of polar phosphate head groups facing water inside and outside the cell, and two non-polar fatty acid tails facing inward, protected from water.
What role does cholesterol play in the plasma membrane?
Cholesterol stabilizes the plasma membrane, especially during temperature changes.
Differentiate between transmembrane and peripheral membrane proteins.
Transmembrane proteins span the entire membrane, while peripheral proteins attach to either the inner or outer membrane surface.
What functions do membrane proteins serve?
Membrane proteins act as channels, receptors, and enzymes.
Where are membrane carbohydrates located and what is their function?
Membrane carbohydrates are only on the outer membrane surface and function in cell-to-cell recognition.
What are glycoproteins and glycolipids?
Glycoproteins are carbohydrates attached to proteins; glycolipids are carbohydrates attached to lipids on the membrane surface.
What is the function of microvilli on the plasma membrane?
Microvilli are folds that increase surface area, important for nutrient absorption.
What is cytoplasm composed of?
Cytoplasm includes the cytosol (viscous fluid) and organelles, filling the space between the plasma membrane and nucleus.
What ions and molecules are found dissolved in the cytosol?
Cytosol contains water, ions like Na+, Cl-, K+, Ca2+, suspended carbohydrates, lipids, and sometimes melanin granules.
Name the non-membranous organelles in the cytoplasm.
Non-membranous organelles include ribosomes, centrosomes, centrioles, and the cytoskeleton.
What is the role of ribosomes?
Ribosomes synthesize proteins and can be free in the cytosol or attached to the rough endoplasmic reticulum.
Describe the centrosome and centrioles.
The centrosome is near the nucleus, containing a matrix and two centrioles, which are cylindrical microtubule structures that direct chromosome movement during cell division.
What are the three types of cytoskeletal protein rods?
Microfilaments (actin), intermediate filaments (tissue-specific), and microtubules (tubulin).
Functions of microfilaments?
Microfilaments maintain cell shape, enable muscle contraction, and support cell movement.
Functions of intermediate filaments?
Intermediate filaments support the cytoplasm and vary by tissue type.
Functions of microtubules?
Microtubules anchor and move organelles, form centrioles, flagella, cilia, and the spindle apparatus during cell division.
What are membranous organelles?
Organelles surrounded by membranes, including mitochondria, endoplasmic reticulum, Golgi apparatus, lysosomes, and peroxisomes.
Describe mitochondria.
Mitochondria have a double membrane, produce ATP, and contain their own DNA, RNA, proteins, and enzymes.
Differentiate rough and smooth endoplasmic reticulum (ER).
Rough ER has ribosomes for protein synthesis; smooth ER stores calcium, detoxifies substances, and synthesizes lipids.
What is the function of the Golgi apparatus?
The Golgi modifies proteins, adds carbohydrates to form glycoproteins, and packages proteins into vesicles for transport or secretion.
What is the nucleus and its main features?
The nucleus is the cell's control center, surrounded by a double membrane with pores, containing chromatin and the nucleolus.
What is the nucleolus?
The nucleolus is inside the nucleus, not membrane-bound, and is the site of ribosome assembly.
Describe the two forms of chromosomes in the nucleus.
Chromosomes appear as thread-like chromatin in non-dividing cells and as condensed, coiled chromosomes in dividing cells.