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AP Chapter 4 part 1

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  • Basal lamina

    A supporting sheet consisting of proteins secreted by epithelial cells, part of the basement membrane.
  • Five distinguishing characteristics of epithelial tissue

    1. Cells bound tightly in sheets 2. Apical and basal surfaces 3. Cells rest on basement membrane 4. Avascular but innervated 5. Capable of rapid cell division.
  • Apical surface of epithelial cells

    The surface facing the exposed outer or inner surface of the organ.
  • Basal surface of epithelial cells

    The surface attached to underlying connective tissue by the basement membrane.
  • Basement membrane composition

    Made up of basal lamina and reticular lamina; reinforces epithelial sheet and resists stretching and tearing.
  • Simple squamous epithelium function and location

    Forms thin membranes for passage of materials; found in air sacs of lungs and lining of heart and blood vessels.
  • Simple cuboidal epithelium function and location

    Adapted for secretion and absorption; found in kidney tubules and pancreatic ducts.
  • Simple columnar epithelium function and location

    Absorbs nutrients and secretes mucus; lines most digestive organs and some exocrine glands.
  • Pseudostratified columnar epithelium features

    Nuclei at varying heights, cells originate from basement membrane, some reach apical surface; secretes and propels mucus.
  • Pseudostratified columnar epithelium location

    Lines trachea, bronchi, and parts of nasal cavity.
  • Stratified squamous epithelium function and location

    Protects against abrasion, drying, and infection; keratinized type in skin epidermis, non-keratinized in mucous membranes.
  • Transitional epithelium function and location

    Allows stretching; found lining urinary bladder, urethra, and ureters.
  • Microvilli

    Finger-like projections forming the brush border; increase surface area for absorption.
  • Cilia

    Short, numerous hair-like appendages that move substances across the cell surface; found in respiratory tract and oviduct.
  • Keratin

    A protein that protects epithelial cells; found in skin, mouth, esophagus, vagina, rectum, hair, nails, and horns.
  • Difference between endocrine and exocrine glands

    Endocrine glands are ductless and secrete hormones into blood; exocrine glands have ducts and secrete onto surfaces or cavities.
  • Examples of endocrine glands

    Pineal gland, pancreas, ovaries, testes, thyroid gland, adrenal gland.
  • Examples of exocrine glands

    Mucous, sweat, oil, salivary glands, liver, pancreas, mammary glands.
  • Multicellular exocrine gland structure

    Composed of a duct and secretory unit, often surrounded by connective tissue forming a capsule and lobes.
  • Classification of exocrine glands by duct structure

    Simple glands have unbranched ducts; compound glands have branched ducts.
  • Classification of exocrine glands by secretory unit shape

    Tubular glands have tube-shaped secretory cells; alveolar glands have sac-shaped secretory cells; tubuloalveolar glands have both.
  • Merocrine mode of secretion

    Secretory vesicles release products by exocytosis without cell damage (e.g., sweat glands, pancreas).
  • Apocrine mode of secretion

    Apical portion of cell pinches off to release secretion; seen in mammary glands.
  • Holocrine mode of secretion

    Entire cell ruptures to release secretion; seen in sebaceous (oil) glands.
  • Carcinoma

    Cancer originating in epithelial tissue; accounts for 80-90% of adult cancers including lung, breast, prostate, and bowel.