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Cell Transport & Permeability - Anatomy & Physiology

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  • Diffusion

    Diffusion is the net, spontaneous movement of particles from an area of higher concentration to an area of lower concentration.

  • Concentration gradient

    The concentration gradient is the difference in the density or amount of a specific substance between two distinct areas.

  • Equilibrium

    Equilibrium is a stable state where particles become evenly distributed, resulting in no further net movement.

  • Kinetic energy in diffusion

    Kinetic energy is the inherent energy of motion in particles that drives random collisions fueling diffusion.

  • Simple diffusion

    Simple diffusion is the unassisted passive movement of small, nonpolar solutes directly through the plasma membrane's lipid bilayer.

  • Facilitated diffusion

    Facilitated diffusion is passive transport of polar or charged molecules across a membrane with the help of specialized membrane proteins.

  • Osmosis

    Osmosis is the net diffusion of water across a selectively permeable membrane toward a higher solute concentration.

  • Hypotonic solution

    A hypotonic solution has a lower concentration of non-penetrating solutes than inside the cell, causing water to enter the cell.

  • Hypertonic solution

    A hypertonic solution has a higher concentration of non-penetrating solutes than inside the cell, causing water to leave the cell.

  • Isotonic solution

    An isotonic solution has an equal concentration of non-penetrating solutes compared to the cell interior, resulting in no net water movement.

  • Tonicity

    Tonicity is the ability of an extracellular solution to change cell volume by driving water movement via osmosis.

  • Crenation

    Crenation is the shrinking or shriveling of a cell due to water loss in a hypertonic environment.

  • Lysis

    Lysis is the bursting of a cell membrane caused by excessive water influx in a hypotonic environment.

  • Active process

    An active process requires cellular energy (ATP) to move substances against their concentration gradient or move large molecules.

  • Passive process

    A passive process moves substances down a concentration gradient without using cellular energy (ATP).

  • Carrier-mediated transport

    Carrier-mediated transport uses specialized membrane proteins to bind and move substances through the lipid bilayer, either passively or actively.

  • Solute vs Solvent

    Solute is the substance dissolved in a solution; solvent is the dissolving medium, usually water in biological systems.

  • Vesicular transport

    Vesicular transport is an active process using membrane-bound vesicles to move bulk fluids or large particles across the cell membrane.

  • Endocytosis

    Endocytosis is vesicular transport where the plasma membrane folds inward to engulf external materials into the cell.

  • Exocytosis

    Exocytosis is vesicular transport where internal vesicles fuse with the plasma membrane to expel materials out of the cell.

  • Difference between active and passive processes

    Active processes require ATP energy; passive processes occur spontaneously without energy use.

  • Difference between simple and facilitated diffusion

    Simple diffusion passes molecules directly through the lipid bilayer; facilitated diffusion requires membrane proteins.

  • Membrane-bound carrier

    A membrane-bound carrier is a transmembrane protein that binds specific solutes to transport them across the membrane.

  • Filtration

    Filtration is passive transport forcing water and small solutes through a membrane or capillary wall by pressure.

  • Driving force behind diffusion

    The driving force behind diffusion is the inherent kinetic energy of atoms or molecules.

  • Effect of solute concentration on diffusion rate

    A higher solute concentration increases gradient steepness, speeding up diffusion; a lower concentration slows it down.

  • Pinocytosis vs Phagocytosis vs Receptor-mediated endocytosis

    Pinocytosis is cell drinking; phagocytosis is cell eating; receptor-mediated endocytosis is selective uptake via ligand-receptor binding.

  • Factors affecting diffusion rate

    Diffusion rate is affected by temperature, molecule size, surface area, membrane permeability, and gradient steepness.