Skip to main content
Back

Cellular Level of Organization - Anatomy & Physiology

Control buttons has been changed to "navigation" mode.
1/44
  • Cell theory

    All living organisms are composed of cells, cells are the basic unit of structure and function, and all cells come from pre-existing cells.

  • Three main parts of a cell

    Plasma membrane, cytoplasm, and nucleus.

  • Extracellular materials in the human body

    Includes extracellular fluid, cellular secretions, and extracellular matrix.

  • Intracellular vs extracellular fluid

    Intracellular fluid is inside cells; extracellular fluid is outside cells, including interstitial fluid which surrounds tissue cells.

  • Plasma membrane structure and function

    A phospholipid bilayer with embedded proteins that controls movement of substances in and out of the cell.

  • Integral proteins

    Proteins embedded within the plasma membrane that function as channels, carriers, receptors, or enzymes.

  • Peripheral proteins

    Proteins attached to the membrane surface involved in signaling, support, and maintaining cell shape.

  • Glycocalyx

    A carbohydrate-rich coating on the cell surface that provides protection and cell recognition.

  • Cell junction general function

    Connect cells to each other and facilitate communication and adhesion.

  • Tight junctions

    Seal adjacent cells tightly to prevent passage of molecules between them.

  • Desmosomes

    Anchoring junctions that bind cells together and resist mechanical stress.

  • Gap junctions

    Channels that allow ions and small molecules to pass directly between cells for communication.

  • Passive vs active transport

    Passive transport requires no energy and moves substances down their concentration gradient; active transport requires energy to move substances against their gradient.

  • Diffusion and its driving force

    Movement of molecules from high to low concentration driven by kinetic energy.

  • Factors influencing diffusion

    Concentration gradient, temperature, and membrane permeability.

  • Selective permeability

    The plasma membrane allows some molecules to pass while blocking others based on size, charge, and solubility.

  • Simple diffusion vs facilitated diffusion

    Simple diffusion passes directly through the membrane; facilitated diffusion uses carrier proteins or channels.

  • Osmosis

    Diffusion of water across a selectively permeable membrane from low to high solute concentration.

  • Isotonic, hypotonic, hypertonic solutions

    Isotonic: no net water movement; Hypotonic: water enters cell causing swelling; Hypertonic: water leaves cell causing shrinkage.

  • Aquaporin

    Protein channels in the membrane that specifically facilitate water movement.

  • Primary vs secondary active transport

    Primary uses ATP directly; secondary uses energy from ion gradients created by primary transport.

  • Vesicular transport

    Movement of large particles or fluids via vesicles, including endocytosis and exocytosis.

  • Receptor-mediated endocytosis

    Selective uptake of molecules using receptors to form vesicles.

  • Resting membrane potential

    Electrical charge difference across the membrane maintained by ion pumps and channels.

  • Cell adhesion molecules and membrane receptors

    Proteins that help cells attach to each other and respond to signals.

  • Cytoplasm and cytosol

    Cytoplasm is the cell contents excluding the nucleus; cytosol is the fluid portion of the cytoplasm.

  • Inclusion

    Non-living substances stored in the cytoplasm like pigments or nutrients.

  • Mitochondria function

    Produce ATP through cellular respiration.

  • Ribosomes function

    Synthesize proteins by translating mRNA.

  • Rough vs smooth endoplasmic reticulum

    Rough ER has ribosomes and synthesizes proteins; smooth ER synthesizes lipids and detoxifies.

  • Golgi apparatus function

    Modifies, sorts, and packages proteins and lipids for transport.

  • Lysosomes function

    Contain enzymes to digest cellular waste and pathogens.

  • Peroxisomes function

    Break down fatty acids and detoxify harmful substances.

  • Endomembrane system

    Network of membranes including ER, Golgi, lysosomes, and vesicles involved in protein and lipid processing.

  • Cytoskeleton function

    Provides structural support, shape, and facilitates cell movement.

  • Centrioles and centrosomes

    Organize microtubules and form the mitotic spindle during cell division.

  • Cilia, flagella, microvilli

    Cilia move substances across the cell surface; flagella propel the cell; microvilli increase surface area for absorption.

  • Nucleus and nucleoli

    Nucleus stores DNA; nucleoli produce ribosomal RNA.

  • Chromatin

    DNA and proteins in a relaxed form within the nucleus.

  • Cytokinesis, mitosis, meiosis

    Cytokinesis divides cytoplasm; mitosis divides somatic cell nucleus; meiosis produces gametes with half chromosome number.

  • Protein synthesis overview

    DNA code stored in nucleus; transcription copies code to mRNA; translation in ribosomes builds proteins from mRNA code.

  • Cell differentiation and stem cells

    Process by which cells become specialized; stem cells can differentiate into various cell types.

  • Atrophy, hypertrophy, hyperplasia

    Atrophy: decrease in cell size; hypertrophy: increase in cell size; hyperplasia: increase in cell number.

  • Necrosis, apoptosis, autophagy

    Necrosis: uncontrolled cell death; apoptosis: programmed cell death; autophagy: self-digestion of cell components.