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Nephron Anatomy & Physiology

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  • What is the nephron?

    The nephron is the functional unit of the kidney responsible for filtering blood and forming urine.

  • What is the function of the glomerulus?

    The glomerulus is a network of capillaries that filters blood plasma into the Bowman’s capsule.

  • What is the Bowman’s capsule?

    The Bowman’s capsule surrounds the glomerulus and collects the filtrate from blood plasma.

  • What is the role of the afferent arteriole?

    The afferent arteriole carries oxygenated blood into the glomerulus for filtration.

  • What does the efferent arteriole do?

    The efferent arteriole carries filtered blood away from the glomerulus.

  • What is the proximal convoluted tubule (PCT)?

    The proximal convoluted tubule reabsorbs water, ions, and nutrients from the filtrate back into the blood.

  • What is the distal convoluted tubule (DCT)?

    The distal convoluted tubule further adjusts the filtrate by selective secretion and reabsorption.

  • What is the Loop of Henle?

    The Loop of Henle creates a concentration gradient in the medulla to concentrate urine.

  • What is the function of the descending limb of the Loop of Henle?

    The descending limb is permeable to water, allowing water to be reabsorbed into the blood.

  • What is the function of the ascending limb of the Loop of Henle?

    The ascending limb is impermeable to water but actively transports ions out to maintain medullary concentration.

  • What is the collecting tubule?

    The collecting tubule collects urine from multiple nephrons and transports it to the renal pelvis.

  • What does the renal artery do?

    The renal artery carries oxygenated blood from the heart to the kidneys.

  • What is the role of the renal vein?

    The renal vein carries oxygen-depleted blood away from the kidneys back to the heart.