Question 1

Which of the following best describes the function of the extracellular matrix (ECM) in tissues?

Accepted Answer

It provides strength to resist tensile and compressive forces, directs cells, regulates cell activity, and holds cells in position.

Question 2

Which type of protein fiber in the ECM is most responsible for resisting tension and pressure?

Accepted Answer

Collagen fibers

Question 3

A tissue sample shows cells tightly packed with little ECM, forming a continuous sheet. Which tissue type is most likely being observed?

Accepted Answer

Epithelial tissue

Question 4

Which cell junction type is most likely to prevent the passage of macromolecules between adjacent cells?

Accepted Answer

Tight (occluding) junctions

Question 5

Which of the following is a function of epithelial tissue that is directly related to its rapid mitotic activity?

Accepted Answer

Protection from mechanical and thermal injury

Question 6

A histological section shows a single layer of flat cells resembling fried eggs. Where is this tissue most likely found?

Accepted Answer

Air sacs of lungs and lining of blood vessels

Question 7

Which of the following best describes paracellular transport across simple epithelia?

Accepted Answer

Substances leak between cells.

Question 8

Which type of epithelial tissue is most likely to be found in areas subject to high mechanical stress, such as the mouth or esophagus?

Accepted Answer

Stratified squamous epithelium

Question 9

Which of the following is a correct pairing of cell type and its function in connective tissue proper?

Accepted Answer

Fibroblasts: produce protein fibers and ground substance

Question 10

Which connective tissue type is most likely to be found deep to the epithelium of the skin and supports blood vessels?

Accepted Answer

Loose (areolar) connective tissue

Question 11

A patient with osteoarthritis is advised to take glucosamine supplements. What is the hypothesized benefit of glucosamine in this context?

Accepted Answer

It increases the production of chondroblasts to slow cartilage degeneration.

Question 12

Which of the following best describes the difference between regeneration and fibrosis in tissue repair?

Accepted Answer

Regeneration replaces damaged cells with cells of the same type, while fibrosis results in scar tissue formation.

Question 13

Which muscle tissue type is characterized by multinucleate cells and voluntary contractions?

Accepted Answer

Skeletal muscle

Question 14

Which of the following is NOT a function of bone tissue?

Accepted Answer

Secretion of hormones into the blood

Question 15

Which of the following statements about neurons is correct?

Accepted Answer

Neurons generate, conduct, and receive nerve impulses.

Question 16

Which type of membrane lines body cavities that do NOT open to the outside of the body and produces serous fluid?

Accepted Answer

Serous membrane

Question 17

Which of the following is a correct description of the basement membrane in epithelial tissue?

Accepted Answer

It anchors epithelial tissue to underlying connective tissue and consists of basal lamina and reticular lamina.

Question 18

Which of the following is a real-world consequence of poor nutrition on tissue repair?

Accepted Answer

Lack of vitamin C impairs collagen synthesis, slowing tissue repair.

Question 19

Which connective tissue cell type is most likely to release histamine and trigger inflammation?

Accepted Answer

Mast cells

Question 20

Which of the following best explains why cardiac muscle tissue generally heals by fibrosis rather than regeneration?

Accepted Answer

Cardiac muscle cells are large and complex, preventing mitosis.

Chapter 4: Histology – The Study of Tissues

Study Guide - Practice Questions