Question 1

Which of the following best describes the difference between paracrine and autocrine signaling in the endocrine system?

Accepted Answer

Paracrine signals act on nearby cells, while autocrine signals act on the same cell that secreted them.

Question 2

A patient is given a drug that blocks all steroid hormone receptors. Which of the following effects would most likely be observed?

Accepted Answer

Decreased transcription of specific genes in target cells.

Question 3

Which of the following equations correctly represents cardiac output ($CO$) in terms of stroke volume ($SV$) and heart rate ($HR$)?

Accepted Answer

$CO = SV 	imes HR$

Question 4

A patient with damage to the posterior pituitary would most likely have difficulty regulating which of the following?

Accepted Answer

Release of oxytocin and antidiuretic hormone (ADH)

Question 5

During the cardiac cycle, which event is most directly responsible for the first heart sound ('lub')?

Accepted Answer

Closure of the atrioventricular (AV) valves

Question 6

Which of the following best explains why steroid hormones typically have a slower onset of action compared to peptide hormones?

Accepted Answer

Steroid hormones bind to intracellular receptors and alter gene transcription, which takes more time.

Question 7

A patient presents with low blood calcium levels. Which endocrine gland is most likely underactive?

Accepted Answer

Parathyroid gland

Question 8

Which of the following best describes the Frank-Starling Law of the heart?

Accepted Answer

The greater the end-diastolic volume ($EDV$), the greater the force of contraction and stroke volume ($SV$).

Question 9

Which of the following is the correct formula for mean arterial pressure ($MAP$)?

Accepted Answer

$MAP = \frac{1}{3} (Systolic\ Pressure) + \frac{2}{3} (Diastolic\ Pressure)$

Question 10

A patient with a tumor in the adrenal cortex is producing excess cortisol. Which of the following would most likely be observed?

Accepted Answer

Increased blood glucose levels and suppressed immune function

Question 11

Which of the following best describes the role of the sinoatrial (SA) node in the heart?

Accepted Answer

It acts as the primary pacemaker, initiating action potentials that set the heart rate.

Question 12

Which of the following would most likely occur if the negative feedback loop between the hypothalamus and anterior pituitary is disrupted?

Accepted Answer

Increased secretion of tropic hormones from the anterior pituitary

Question 13

A patient is experiencing excessive urination and dehydration due to a lack of antidiuretic hormone (ADH). Which condition does this most likely indicate?

Accepted Answer

Diabetes insipidus

Question 14

Which of the following best explains why veins have valves, while arteries generally do not?

Accepted Answer

Valves in veins prevent backflow of blood due to lower pressure and gravity.

Question 15

Which of the following hormones is secreted by the pineal gland and helps regulate circadian rhythms?

Accepted Answer

Melatonin

Question 16

If a patient has a blood pressure of 120/80 mmHg, what is their pulse pressure?

Accepted Answer

$40\ mmHg$

Question 17

Which of the following best describes the effect of increased sympathetic nervous system activity on the heart?

Accepted Answer

Increased heart rate and increased contractility

Question 18

A patient with a blocked left anterior descending (LAD) artery is at risk for which of the following?

Accepted Answer

Reduced blood flow to the anterior wall of the left ventricle

Question 19

Which of the following is the primary function of aldosterone secreted by the adrenal cortex?

Accepted Answer

Promote sodium reabsorption in the kidneys

Question 20

Which of the following best describes the relationship between vessel diameter and resistance to blood flow?

Accepted Answer

Resistance decreases as vessel diameter increases.

Core Concepts in Endocrine and Cardiovascular Systems: Anatomy & Physiology Study Guide

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