Question 1

Which of the following best describes the primary function of skeletal muscle tissue?

Accepted Answer

To move bones and facilitate voluntary body movements

Question 2

Which connective tissue sheath surrounds an individual muscle fiber?

Accepted Answer

Endomysium

Question 3

A patient is diagnosed with a disease that destroys acetylcholine (ACh) receptors at the neuromuscular junction. Which of the following symptoms would most likely be observed?

Accepted Answer

Progressive muscle weakness and fatigue

Question 4

Which of the following is a distinguishing microscopic feature of cardiac muscle tissue?

Accepted Answer

Branching chains of cells with intercalated discs and striations

Question 5

During the process of skeletal muscle contraction, which neurotransmitter is released at the neuromuscular junction?

Accepted Answer

Acetylcholine

Question 6

Which of the following equations best represents the relationship between force ($F$), mass ($m$), and acceleration ($a$) as applied to skeletal muscle contraction?

Accepted Answer

$F = m 	imes a$

Question 7

A muscle is composed of several fascicles. Each fascicle is surrounded by which connective tissue layer?

Accepted Answer

Perimysium

Question 8

Which type of muscle tissue is primarily responsible for peristalsis in the digestive tract?

Accepted Answer

Smooth muscle

Question 9

If a skeletal muscle fiber is unable to repolarize after an action potential, which ion channel is most likely malfunctioning?

Accepted Answer

Voltage-gated K$^+$ channel

Question 10

Which of the following best explains why skeletal muscle fibers appear striated under the microscope?

Accepted Answer

The regular arrangement of thick and thin myofilaments

Question 11

A patient with Duchenne Muscular Dystrophy (DMD) is unable to produce dystrophin, a protein that stabilizes the sarcolemma. Which of the following is a likely consequence?

Accepted Answer

Progressive muscle fiber degeneration and weakness

Question 12

Which of the following best describes the role of the sarcoplasmic reticulum in skeletal muscle contraction?

Accepted Answer

It stores and releases Ca$^{2+}$ ions

Question 13

During the sliding filament model of contraction, which event occurs immediately after Ca$^{2+}$ binds to troponin?

Accepted Answer

Tropomyosin shifts to expose myosin-binding sites on actin

Question 14

Which of the following is true regarding the organization of skeletal muscle from largest to smallest structure?

Accepted Answer

Muscle > Fascicle > Muscle fiber > Myofibril

Question 15

A researcher applies a drug that blocks voltage-gated Na$^+$ channels in skeletal muscle. What is the most immediate effect on muscle contraction?

Accepted Answer

Action potentials cannot be generated, so contraction is inhibited

Question 16

Which of the following best describes the difference between skeletal and smooth muscle cells?

Accepted Answer

Skeletal muscle cells are multinucleate and striated; smooth muscle cells are uninucleate and non-striated

Question 17

Which of the following scenarios best illustrates the function of perimysium?

Accepted Answer

A weightlifter's muscle fascicles are bundled together by a connective tissue sheath

Question 18

Which of the following best explains why cardiac muscle can contract rhythmically without direct nervous stimulation?

Accepted Answer

It contains pacemaker cells that generate spontaneous action potentials

Question 19

A patient is experiencing muscle weakness due to an autoimmune attack on acetylcholine receptors. Which disease is most likely responsible?

Accepted Answer

Myasthenia Gravis

Question 20

Which of the following best describes the sequence of events at the neuromuscular junction leading to muscle contraction?

Accepted Answer

Action potential arrives at axon terminal → Ca$^{2+}$ enters neuron → ACh released → ACh binds to receptors on sarcolemma → Na$^+$ enters muscle fiber → Action potential generated in muscle fiber

Muscles and Muscle Tissue: Structure, Types, and Organization

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