Question 1

Which of the following is NOT a primary function of the skeletal system?

Accepted Answer

Digestion of nutrients

Question 2

A patient with a genetic defect in collagen synthesis is most likely to experience which of the following bone problems?

Accepted Answer

Bones that are brittle and fracture easily

Question 3

Which bone type is correctly matched with its description?

Accepted Answer

Flat bone: thin and broad

Question 4

During endochondral ossification, what is the correct sequence of events?

Accepted Answer

Cartilage model forms → bone collar forms → primary ossification center develops → medullary cavity forms → secondary ossification centers develop

Question 5

Which of the following best explains why bones are able to resist compression forces?

Accepted Answer

Hydroxyapatite crystals in the inorganic matrix

Question 6

A 10-year-old child suffers a fracture at the epiphyseal plate. What is the most likely consequence if the injury is not properly treated?

Accepted Answer

Disrupted bone growth in length

Question 7

Which of the following statements about osteoclasts is correct?

Accepted Answer

Osteoclasts secrete $ \mathrm{H}^+ $ and enzymes to break down bone matrix

Question 8

Which of the following best describes the structure of flat bones?

Accepted Answer

A sandwich of spongy bone between two layers of compact bone

Question 9

A patient with chronic low blood calcium levels may have impaired function of which bone cell type?

Accepted Answer

Osteoclasts

Question 10

Which of the following equations correctly represents the chemical formula for hydroxyapatite, the main inorganic component of bone?

Accepted Answer

$ \mathrm{Ca}_5(\mathrm{PO}_4)_3(\mathrm{OH}) $

Question 11

Which process is responsible for the formation of most bones below the skull (excluding the clavicle)?

Accepted Answer

Endochondral ossification

Question 12

Which of the following best explains why spongy bone is found at the ends of long bones?

Accepted Answer

It provides a lightweight structure and resists forces from multiple directions

Question 13

A patient with a mutation that prevents the formation of Sharpey's fibers would most likely have problems with which of the following?

Accepted Answer

Attachment of periosteum to bone

Question 14

Which of the following is a correct comparison between intramembranous and endochondral ossification?

Accepted Answer

Intramembranous ossification forms flat bones of the skull, while endochondral ossification forms most bones below the skull

Question 15

Which of the following best describes the role of red bone marrow?

Accepted Answer

Site of hematopoiesis

Question 16

A 35-year-old patient has a bone biopsy showing a deficiency in proteoglycans and glycosaminoglycans. Which property of bone is most likely to be affected?

Accepted Answer

Ability to maintain hydration and flexibility

Question 17

Which of the following best explains the difference between osteoblasts and osteocytes?

Accepted Answer

Osteoblasts build bone matrix and mature into osteocytes, which maintain bone matrix

Question 18

Which of the following is a real-life example of the skeletal system's role in acid-base homeostasis?

Accepted Answer

Bones release $ \mathrm{Ca}^{2+} $ and $ \mathrm{PO}_4^{3-} $ ions to buffer blood pH during metabolic acidosis

Question 19

Which of the following best describes the arrangement of lamellae in compact bone?

Accepted Answer

Concentric rings around a central canal

Question 20

A patient with a disease that destroys the endosteum would have difficulty with which of the following processes?

Accepted Answer

Bone resorption by osteoclasts

Skeletal System: Structure, Function, and Bone Histology

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