How does spontaneity relate to the equilibrium constant in biochemical reactions?

• A. Spontaneity is indicated by a negative Gibbs free energy change, which often correlates with a large equilibrium constant.
• B. Spontaneity is indicated by a zero Gibbs free energy change.
• C. Spontaneity is unrelated to the equilibrium constant.
• D. Spontaneity is indicated by a positive Gibbs free energy change, which often correlates with a small equilibrium constant.

Answer: (A)