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How does natural selection favor heterozygous individuals for the sickle cell trait in areas with high malaria prevalence?
Why does the hydrophobic effect cause hemoglobin molecules to agglutinate in sickle cell anemia?
Describe how chymotrypsin stabilizes the transition state during peptide bond cleavage.
Evaluate the effectiveness of chymotrypsin's mechanism in terms of Michaelis-Menten kinetics.
What is the role of hydrogen bonding in the catalytic triad of chymotrypsin?
Chymotrypsin targets which type of peptide bond during the acylation phase?
Which amino acid residue does chymotrypsin recognize for cleavage?
Which phase involves the hydrolysis of the ester linkage?
What is the primary function of glycogen phosphorylase in glycogen metabolism?
Which statement accurately compares the liver and muscle isozymes of glycogen phosphorylase?
How does the phosphorylation state of serine residues affect the catalytic activity of glycogen phosphorylase?
What is the primary role of glycogen breakdown in the liver?
What is the default state of liver glycogen phosphorylase and its significance?