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Biochemistry Midterm - Part 7 of 7
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Problem 1
Problem 2
Problem 3
Problem 4
Problem 5
Problem 6
Problem 7
Problem 8
Problem 9
Problem 10
Problem 11
Problem 12
Problem 13
Problem 14
Problem 15
Problem 16
Problem 17
Problem 18
Problem 19
Problem 20
Problem 21
Problem 22
Problem 23
Problem 24
Problem 25
Biochemistry Midterm - Part 7 of 7
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8. Protein Function / Chymotrypsin's Catalytic Mechanism / Problem 18
Problem 18
During the nucleophilic attack in the acylation phase, what role does histidine 57 play?
A
Acts as an acid to donate a proton to serine 195
B
Acts as a base to deprotonate serine 195
C
Forms a covalent bond with the substrate
D
Stabilizes the tetrahedral intermediate
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