Synthesize how the degree of inhibition (α and α') modifies the Lineweaver-Burk equation in the presence of mixed inhibitors.

• A. Neither α nor α' affect the Lineweaver-Burk equation.
• B. Both α and α' increase the slope and alter the intercepts, reflecting changes in K_m and V_max.
• C. Only α affects the slope, while α' affects the intercepts.
• D. Both α and α' decrease the slope and intercepts, indicating reduced enzyme efficiency.

Answer: (B)