In a dideoxy sequencing experiment, what would be the result of using equal concentrations of dNTPs and ddNTPs?

• A. DNA synthesis would proceed normally without termination.
• B. DNA synthesis would frequently terminate, resulting in very short fragments.
• C. The sequencing reaction would fail to initiate.
• D. The DNA fragments would be too long to separate by gel electrophoresis.

Answer: (B)