Analyze the differences between the enzymes that reverse reactions 10, 3, and 1 of glycolysis during gluconeogenesis.

• A. All three reactions are reversed by the same enzyme, pyruvate carboxylase.
• B. Reactions 10, 3, and 1 are reversed by hexokinase, phosphofructokinase, and pyruvate kinase, respectively.
• C. Reactions 10, 3, and 1 are reversed by pyruvate carboxylase, fructose 1,6-bisphosphatase, and glucose 6-phosphatase, respectively.
• D. Reactions 10, 3, and 1 are reversed by glucose 6-phosphatase only.

Answer: (C)