How might lipid hormones influence metabolic responses when they bind to intracellular receptors?

• A. By preventing any changes in gene expression.
• B. By directly altering gene transcription, leading to changes in enzyme production and metabolic pathways.
• C. By binding to extracellular receptors and initiating a second messenger cascade.
• D. By only affecting the cell surface without entering the cell.

Answer: (B)