A patient consumes a glucose-rich meal. Describe the transition of liver Glycogen Phosphorylase a in response to this event.

• A. The enzyme remains in its active r state, continuing to break down glycogen.
• B. The enzyme transitions to an intermediate state, partially active.
• C. The enzyme transitions to a permanently inactive state, ceasing all activity.
• D. The enzyme transitions from its active r state to the inactive t state due to negative feedback from glucose.

Answer: (D)