Which cleavage method should be used to target specific peptide bonds in a protein?

• A. Peptidase cleavage, because it cleaves randomly.
• B. Chemical cleavage, due to its specificity for certain peptide bonds.
• C. Use both chemical and peptidase cleavage for best results.
• D. Amino acid hydrolysis, because it cleaves all peptide bonds.

Answer: (B)