What could be the effect of a mutation that prevents autophosphorylation in RTKs?

• A. RTKs will continuously activate without ligand binding.
• B. RTKs will function normally despite the mutation.
• C. RTKs will not be fully activated, impairing their ability to phosphorylate target proteins.
• D. RTKs will bind ligands but fail to dimerize.

Answer: (C)