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Stimulatory Adenylate Cyclase GPCR Signaling
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Stimulatory Adenylate Cyclase GPCR Signaling
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12. Biosignaling / Stimulatory Adenylate Cyclase GPCR Signaling / Problem 1
Problem 1
In a scenario where the GDP to GTP exchange in the stimulatory G protein is inhibited, what would be the immediate consequence in the signaling pathway?
A
The GPCR would undergo a conformational change without ligand binding.
B
The alpha subunit would remain inactive and unable to dissociate from the beta gamma subunits.
C
Protein kinase A would be activated without the need for cyclic AMP.
D
Adenylate cyclase would be activated directly by the beta gamma subunits.
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