How does initial reaction velocity (V0) differ from Vmax in terms of substrate concentration?

• A. V0 occurs at saturating substrate concentrations, while Vmax occurs at lower substrate concentrations.
• B. V0 occurs at lower substrate concentrations, while Vmax occurs at saturating substrate concentrations.
• C. V0 and Vmax occur at the same substrate concentration.
• D. V0 is independent of substrate concentration, while Vmax depends on it.

Answer: (B)