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Protein-Ligand Binding and Oxygen Transport: Hemoglobin and Myoglobin

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Introduction to Protein-Ligand Interactions

Protein-Ligand Equilibrium Constants

Protein-Ligand Fractional Saturation

Myoglobin vs. Hemoglobin

Heme Prosthetic Group

Hemoglobin Cooperativity

Hill Equation

Hill Plot

Bohr Effect

BPG Regulation of Hemoglobin

Sickle Cell Anemia