Cellular Respiration and Metabolism - General Biology
Terms in this set (20)
Metabolism is the sum of all chemical reactions in a cell, including both catabolic and anabolic reactions.
Catabolic reactions break down molecules and release energy, while anabolic reactions build molecules and require energy.
Exergonic reactions release energy; endergonic reactions require energy. They are often coupled in metabolism.
Enzymes speed up metabolic reactions by lowering activation energy and are specific to substrates.
ATP has three phosphate groups with high-energy bonds; it stores and releases energy for cellular processes.
ATP loses a phosphate group to become ADP, releasing energy; ADP can be phosphorylated back to ATP using energy.
Redox reactions involve the transfer of electrons; oxidation is loss of electrons, reduction is gain of electrons.
NAD+ and FAD accept electrons (are reduced) to NADH and FADH2, transporting energy in cellular respiration.
\(\mathrm{C_6H_{12}O_6 + 6 O_2 \rightarrow 6 CO_2 + 6 H_2O + \sim 36 ATP}\)
Glycolysis occurs in the cytoplasm; it converts glucose into 2 pyruvate, producing 2 ATP (net) and 2 NADH.
Pyruvate is transported into the mitochondria and converted to acetyl CoA, producing 2 NADH and releasing CO2.
Occurs in mitochondrial matrix; acetyl CoA is broken down, producing 2 ATP, 6 NADH, 2 FADH2, and releasing CO2.
ATP synthesis where a phosphate group is directly transferred from a substrate to ADP, occurring in glycolysis and Krebs cycle.
ETC uses electrons from NADH and FADH2 to pump protons across the inner mitochondrial membrane, creating a gradient.
Protons flow back through ATP synthase, using proton motive force to synthesize ATP from ADP and phosphate.
Oxygen is the final electron acceptor in the ETC, allowing electrons to flow and ATP production to continue.
Aerobic respiration requires oxygen; anaerobic respiration (fermentation) does not and regenerates NAD+ for glycolysis.
Fermentation regenerates NAD+ in the absence of oxygen, allowing glycolysis to continue producing ATP.
Alcohol fermentation produces ethanol and CO2 (used by yeast); lactic acid fermentation produces lactic acid (used by bacteria and muscles).
Feedback inhibition controls enzyme activity; high ATP levels inhibit enzymes, while low ATP levels activate them.