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General Biology Final Exam Study Guide

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  • Meiosis

    Meiosis is a type of cell division that reduces the chromosome number by half, producing four haploid cells. It includes two stages: Meiosis I and Meiosis II.

  • Differences between meiosis and mitosis

    Meiosis produces four genetically unique haploid cells, while mitosis produces two identical diploid cells. Meiosis involves two divisions; mitosis only one.

  • Genetic variation in meiosis

    Genetic variation arises from independent assortment, crossing over, and random fertilization during meiosis.

  • Crossing over

    Crossing over is the exchange of genetic material between homologous chromosomes during prophase I of meiosis, increasing genetic diversity.

  • Nondisjunction

    Nondisjunction is a mistake during meiosis where chromosomes fail to separate properly, leading to abnormal chromosome numbers.

  • Karyotype

    A karyotype is a visual profile of an individual's chromosomes, used to detect chromosomal abnormalities.

  • Alterations of chromosome structure

    Chromosome alterations include deletions, duplications, inversions, and translocations.

  • Mendelian Genetics

    Mendelian genetics studies inheritance patterns based on dominant and recessive alleles following Mendel's laws.

  • Non-Mendelian inheritance

    Includes multiple alleles, codominance, incomplete dominance, and sex-linked inheritance.

  • Genotype vs Phenotype

    Genotype is the genetic makeup; phenotype is the observable trait.

  • Punnett Squares

    Punnett squares predict offspring genotypes in monohybrid and dihybrid crosses.

  • DNA structure

    DNA is composed of nucleotides with a sugar, phosphate group, and nitrogenous bases (A, T, G, C).

  • Chargaff's Rule

    Chargaff's rule: In DNA, A = T and G = C.

  • Key enzymes in DNA replication

    Helicase unwinds DNA, primase adds RNA primers, DNA polymerase synthesizes new strands, and ligase joins Okazaki fragments.

  • Leading vs Lagging strand

    The leading strand is synthesized continuously; the lagging strand is synthesized in Okazaki fragments.

  • Functions of mRNA, tRNA, and rRNA

    mRNA carries the genetic code, tRNA brings amino acids, and rRNA forms the ribosome.

  • Stages of transcription

    Transcription stages: initiation (RNA polymerase binds promoter), elongation (RNA strand grows), termination (RNA polymerase reaches terminator).

  • RNA processing in eukaryotes

    Eukaryotic RNA undergoes splicing to remove introns and join exons. Prokaryotic RNA is not processed.

  • Stages of translation

    Translation stages: initiation (ribosome assembles), elongation (amino acids added), termination (stop codon reached).

  • Types of mutations

    Mutations include silent, missense, nonsense, and frameshift mutations.

  • Darwin and Wallace's theory of evolution

    Evolution occurs by natural selection, where organisms with advantageous traits survive and reproduce.

  • Evidence for evolution

    Includes morphological, geographical, fossil, embryological, and DNA evidence.

  • Homologous vs Analogous structures

    Homologous structures share common ancestry; analogous structures have similar function but different origins.

  • Hardy-Weinberg equilibrium

    Population is in equilibrium if p + q = 1 and p^2 + 2pq + q^2 = 1, with no evolution occurring.

  • Genetic drift

    Genetic drift is random changes in allele frequencies, including bottleneck and founder effects.

  • Types of natural selection

    Includes directional, stabilizing, disruptive, and sexual selection.

  • Sympatric vs Allopatric speciation

    Allopatric speciation occurs with geographic separation; sympatric occurs without geographic separation.

  • Biotic and abiotic factors

    Biotic factors are living components; abiotic factors are nonliving environmental components.

  • Symbiotic relationships

    Types include mutualism, parasitism, and commensalism.

  • Energy flow in ecosystems

    Energy flows through producers, consumers, and decomposers with about 10% energy transfer efficiency.