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General Biology: Genetics and Molecular Biology

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  • What is Gregor Mendel known for?

    Gregor Mendel is known as the father of genetics for discovering the basic principles of heredity through pea plant experiments.

  • Define a gene.

    A gene is a segment of DNA that contains the instructions to make a specific protein or RNA molecule.

  • What is DNA composed of?

    DNA is composed of nucleotides, each containing a sugar, phosphate group, and one of four nitrogenous bases: adenine, thymine, cytosine, or guanine.

  • What is the central dogma of molecular biology?

    The central dogma describes the flow of genetic information: DNA is transcribed into RNA, which is then translated into protein.

  • What happens during transcription?

    Transcription is the process where a DNA sequence is copied into messenger RNA (mRNA) by RNA polymerase.

  • What is the role of mRNA in gene expression?

    mRNA carries the genetic code from DNA in the nucleus to the ribosomes in the cytoplasm for protein synthesis.

  • Describe translation in protein synthesis.

    Translation is the process where ribosomes read mRNA codons to assemble amino acids into a polypeptide chain (protein).

  • What is a codon?

    A codon is a sequence of three nucleotides on mRNA that specifies a particular amino acid.

  • How do Mendel's laws relate to genes?

    Mendel's laws explain how genes are inherited independently and segregate during gamete formation.

  • What base pairs with adenine in DNA?

    In DNA, adenine pairs with thymine via two hydrogen bonds.

  • What base pairs with adenine in RNA?

    In RNA, adenine pairs with uracil instead of thymine.

  • What enzyme synthesizes RNA during transcription?

    RNA polymerase synthesizes RNA by reading the DNA template strand.

  • What is the function of tRNA in translation?

    tRNA brings specific amino acids to the ribosome matching its anticodon to the mRNA codon.

  • What is a phenotype?

    A phenotype is the observable physical or biochemical characteristics of an organism determined by its genotype and environment.

  • What is a genotype?

    A genotype is the genetic makeup of an organism, the specific alleles it carries.

  • What is an allele?

    An allele is a variant form of a gene that can produce different traits.

  • What is the significance of the genetic code being universal?

    The genetic code is nearly universal, meaning most organisms use the same codons to specify amino acids, allowing gene transfer between species.

  • What is the role of ribosomes in translation?

    Ribosomes are the molecular machines that facilitate the assembly of amino acids into proteins by reading mRNA.

  • What is the difference between DNA and RNA?

    DNA is double-stranded with deoxyribose sugar and thymine; RNA is single-stranded with ribose sugar and uracil.

  • What is a mutation?

    A mutation is a change in the DNA sequence that can affect gene function and lead to variation or disease.