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General Biology Key Concepts

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  • Biosphere

    Biosphere is the global ecosystem including all living organisms and their interactions with the atmosphere and environment.

  • Difference between Eukaryotic and Prokaryotic cells

    Eukaryotic cells have membrane-bound organelles and a nucleus; Prokaryotic cells lack a nucleus and membrane-bound organelles and are generally smaller.

  • Gene

    Gene is a unit of inheritance, a section of DNA on a chromosome that codes for a specific protein or function.

  • Gene expression

    Gene expression is the process of converting information from a gene into its cellular product, typically a protein, often using RNA as an intermediary.

  • Energy flow in ecosystems

    Energy flows through ecosystems entering as light and exiting as heat, while chemicals are recycled within the ecosystem.

  • Evolution

    Evolution is biological change where organisms gain heritable differences from ancestors, showing descent from a common ancestor.

  • Scientific method steps

    Observation, question, hypothesis (testable explanation), prediction, experiment, analysis, and conclusion.

  • Atomic number and mass number

    Atomic number is the number of protons; mass number is the sum of protons and neutrons in an atom.

  • Ionic vs Covalent bonds

    Ionic bonds transfer electrons between atoms; Covalent bonds share pairs of valence electrons between atoms.

  • Water's high specific heat

    Water absorbs or releases large amounts of heat with little temperature change due to breaking and forming hydrogen bonds.

  • Four classes of macromolecules

    Carbohydrates, lipids, proteins, and nucleic acids are the four major classes of biological macromolecules.

  • Primary structure of protein

    The unique sequence of amino acids in a polypeptide chain.

  • Cell organelles involved in protein synthesis

    Ribosomes synthesize proteins; rough ER has ribosomes and helps secrete glycoproteins.

  • Mitochondria function

    Site of cellular respiration, converting oxygen and organic molecules into ATP energy.

  • Fluid mosaic model

    Describes the plasma membrane as a mosaic of proteins floating in or on a fluid lipid bilayer.

  • Passive vs Active transport

    Passive transport requires no energy and moves substances down their concentration gradient; active transport requires energy to move substances against their gradient.

  • Tonicity

    Ability of a solution to cause a cell to gain or lose water: isotonic (no net movement), hypertonic (cell loses water), hypotonic (cell gains water).

  • Stages of cellular respiration

    Glycolysis, pyruvate oxidation and citric acid cycle, and oxidative phosphorylation (ETC and chemiosmosis).

  • Photosynthesis main processes

    Light reactions occur in thylakoid membranes producing ATP and NADPH; Calvin cycle occurs in stroma fixing CO2 into sugars.

  • Mitosis phases

    Prophase, prometaphase, metaphase, anaphase, telophase, followed by cytokinesis.

  • Difference between mitosis and meiosis

    Mitosis produces genetically identical diploid cells; meiosis produces genetically diverse haploid gametes through two divisions.

  • Mendel's Law of Segregation

    Two alleles for a gene separate during gamete formation, so each gamete carries only one allele.

  • DNA replication direction

    New DNA strands are synthesized in the 5’ to 3’ direction, antiparallel to the template strand.

  • Central dogma of molecular biology

    DNA is transcribed into RNA, which is translated into protein.

  • Types of mutations

    Point mutations include silent, missense, nonsense; insertions or deletions can cause frameshifts.

  • Operon function

    Operons regulate gene expression by switching genes on or off via operator and promoter regions.

  • Epigenetic inheritance

    Transmission of gene expression changes without altering the DNA sequence, often via DNA methylation or histone modification.

  • Hardy-Weinberg equilibrium conditions

    No evolution occurs if there is random mating, no mutations, no natural selection, large population size, and no gene flow.

  • Natural selection types

    Directional, disruptive, and stabilizing selection affect allele frequencies by favoring different phenotypes.