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Mendelian Genetics and Inheritance Patterns

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  • What is heredity?

    Heredity is the transmission of traits from one generation to the next.

  • Define character and trait in genetics.

    A character is a heritable feature that varies among individuals, and a trait is a variant of that character.

  • What are alleles?

    Alleles are alternative versions of genes that determine heritable traits.

  • What is a true-breeding plant?

    A true-breeding plant is one that, when self-fertilized, produces offspring with the same trait for many generations.

  • What is the P generation in Mendel's experiments?

    The P generation refers to the true-breeding parental plants used in Mendel's crosses.

  • What is a monohybrid cross?

    A monohybrid cross is a cross between two individuals differing in a single character.

  • State Mendel's Law of Segregation.

    Allele pairs separate during gamete formation, so each gamete carries only one allele for each character.

  • What is the difference between genotype and phenotype?

    Genotype is the genetic makeup (allele combination), while phenotype is the physical expression of a trait.

  • Define homozygous and heterozygous.

    Homozygous individuals have two identical alleles; heterozygous individuals have two different alleles for a character.

  • What is dominance in alleles?

    Dominant alleles determine the organism's appearance with one copy; recessive alleles have no effect unless two copies are present.

  • What is a Punnett square used for?

    A Punnett square is a diagram used to predict the possible allele combinations from a genetic cross.

  • What is a dihybrid cross?

    A dihybrid cross follows the inheritance of two different characters simultaneously.

  • State Mendel's Law of Independent Assortment.

    Alleles for different genes assort independently during gamete formation, leading to random combinations.

  • What phenotypic ratio results from a dihybrid cross with independent assortment?

    The typical phenotypic ratio is \(9:3:3:1\) for the F2 generation.

  • What is a testcross?

    A testcross is a mating between an individual with an unknown genotype and a homozygous recessive individual to determine the unknown genotype.

  • How is probability used in genetics?

    Probability predicts the likelihood of specific genotypes or phenotypes occurring in offspring based on allele combinations.

  • What is incomplete dominance?

    Incomplete dominance occurs when the heterozygote's phenotype is intermediate between the two homozygotes.

  • What is codominance?

    Codominance occurs when both alleles in a heterozygote are fully expressed separately.

  • How many alleles control human ABO blood type?

    Three alleles (IA, IB, and i) control ABO blood type, with IA and IB codominant and both dominant over i.

  • What is pleiotropy?

    Pleiotropy occurs when one gene influences multiple phenotypic traits, such as the hemoglobin gene in sickle-cell disease.

  • What is polygenic inheritance?

    Polygenic inheritance is when multiple genes contribute additively to a single phenotypic character, producing a range of phenotypes.

  • How do linked genes affect inheritance?

    Linked genes are located close together on the same chromosome and tend to be inherited together, violating independent assortment.

  • What role does crossing over play in linked genes?

    Crossing over during meiosis can separate linked genes, producing recombinant gametes with new allele combinations.

  • What are sex-linked genes?

    Sex-linked genes are genes located on sex chromosomes, often showing unique inheritance patterns, such as X-linked recessive traits.

  • Why are X-linked recessive disorders more common in males?

    Males have only one X chromosome, so a single recessive allele causes the disorder; females need two copies to be affected.