How might the presence of a hydrophobic pocket in a protein binding site affect ligand binding?

A new drug is designed to inhibit an enzyme involved in cancer cell proliferation. What is a potential consequence of this drug on the enzyme's activity?

Which type of bond is primarily responsible for the interaction between proteins and ligands?

A sudden increase in intracellular calcium concentration is observed. How might this affect calcium-binding proteins and cellular signaling?

What distinguishes N-linked glycosylation from O-linked glycosylation?

How does ubiquitylation specifically target proteins for degradation?

Which of the following is a key difference between the ubiquitin-proteasome pathway and the lysosomal pathway?

What is a potential consequence of misfolded proteins accumulating in a cell?

What is the role of E3 enzymes in the ubiquitin-proteasome pathway?