A patient is diagnosed with an autoimmune disease. Which aspect of B cell function is likely compromised?

• A. Clonal selection, resulting in insufficient antibody production.
• B. Memory cell formation, leading to repeated infections.
• C. Antigen specificity, causing B cells to produce antibodies against multiple pathogens.
• D. Self-tolerance, leading to the production of antibodies against the body's own tissues.

Answer: (D)