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ER Processing and Transport
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ER Processing and Transport
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13. Intracellular Protein Transport / ER Processing and Transport / Problem 5
Problem 5
Design an experiment to test the role of the SRP in co-translational import of proteins into the ER.
A
Assess the formation of disulfide bonds in proteins in cells with and without SRP.
B
Use a mutant cell line lacking SRP and compare protein localization to wild-type cells.
C
Measure the rate of GTP hydrolysis in cells with and without SRP.
D
Compare the glycosylation patterns of proteins in cells with and without SRP.
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