Analyze the impact of histone acetylation on nucleosome structure and function.

• A. Histone acetylation has no impact on nucleosome structure.
• B. Histone acetylation leads to the degradation of histones.
• C. Histone acetylation decreases the positive charge of histones, reducing DNA binding and increasing accessibility.
• D. Histone acetylation increases the positive charge of histones, enhancing DNA binding.

Answer: (C)