What is the role of PTEN phosphatase in phosphoinositide signaling pathways?

• A. PTEN phosphatase removes phosphates from phosphoinositol lipids, inactivating the signaling pathway.
• B. PTEN phosphatase inhibits protein kinase C, reducing calcium signaling.
• C. PTEN phosphatase directly produces IP3 and DAG.
• D. PTEN phosphatase adds phosphates to phosphoinositol lipids, activating the signaling pathway.

Answer: (A)