How do transcriptional activators and repressors interact with coactivators and corepressors?

• A. They directly bind to DNA sequences to initiate transcription.
• B. They degrade RNA polymerase to stop transcription.
• C. They are involved in the translation process.
• D. They interact to facilitate or inhibit transcription by altering chromatin structure or interacting with RNA polymerase.

Answer: (D)