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Key Proteins and Functions in Replication

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  • Helicase


    Unwinds DNA double helix

  • Topoisomerase


    Relieves supercoiling strain

  • Single Stranded binding proteins


    Stabilizes unwound DNA

  • Primase


    Synthesizes RNA Primer

  • DNA polymerase


    Synthesizes RNA primer

  • DNA Clamp


    Increases processivity

  • DNA ligase


    Joins Okazaki fragments

  • Telomerase


    Extends telomeres

  • mRNA


    Template for protein synthesis

  • tRNA


    Transfers amino acids to ribosome

  • rRNA


    Forms ribosome, catalyzes translation