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L9) Methods to degrade proteins & 1 other concept

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  • Autophagy


    "Eating of self"

    • removes misfolded/aggregated proteins -->

      • clears damaged organelles EX: mitochondria

  • Proteasomes


    Breaks down (degrades) unfolded/unneed proteins

    • process is call --> proteolysis

  • Lysosomes


    Organelle in the cell that acts as a garbage disposal to degrade (break down)

    • AKA recycle center

  • 1) Denaturation


    when a protein loses its shape and stops working

    • caused by high heat, strong acids/bases,

      • protein unwinds