IndietroAtoms, Molecules, and Biochemistry Foundations in Anatomy & Physiology
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Matter
Definition and States of Matter
Matter is anything that has mass and occupies space. It is the fundamental substance of the universe and forms the basis for all physical objects, including those in the human body.
Three States of Matter: Solid, liquid, and gas.
Chemistry: The study of matter and its interactions.
Atoms and Atomic Structure
Properties and Structure of Atoms
An atom is the smallest unit of matter that retains the properties of an element. Atoms are composed of subatomic particles and are the building blocks of all substances.
Subatomic Particles:
Protons (p+): Found in the nucleus, positively charged.
Neutrons (n): Found in the nucleus, no charge.
Electrons (e-): Found in electron shells surrounding the nucleus, negatively charged.
Electron Shells: Regions around the nucleus where electrons exist.
First shell: Can hold 2 electrons.
Second shell: Can hold 8 electrons.
Third shell: Can hold 18 electrons (with additional info: shells fill in order of increasing energy).
Elements in the Periodic Table and the Human Body
Elements and Atomic Number
Elements are pure substances that cannot be broken down by chemical means. Each element is defined by its atomic number, which is the number of protons in its nucleus.
Periodic Table: Lists elements by atomic number and organizes them into groups with similar properties.
Chemical Symbol: Each element is represented by a unique symbol.
Major Elements in the Human Body:
Oxygen (O)
Carbon (C)
Hydrogen (H)
Nitrogen (N)
Isotopes and Radioactivity
Isotopes and Atomic Mass
Isotopes are atoms of the same element with the same number of protons but different numbers of neutrons, resulting in different mass numbers. Some isotopes are radioactive and can emit energy.
Atomic Mass: Equal to the sum of all protons and neutrons in the nucleus.
Radioactive Isotopes: Unstable isotopes that emit radiation as they decay.
Mixtures
Types of Mixtures
Mixtures are combinations of two or more substances that are physically blended but not chemically bonded.
Solution: Homogeneous mixture where particles are evenly distributed.
Solvent: Substance that dissolves another substance.
Solute: Substance that is dissolved.
Chemical Bonds
Types of Chemical Bonds
Chemical bonds are forces that hold atoms together in molecules and compounds. They are essential for the structure and function of biological molecules.
Ionic Bonds: Formed when electrons are transferred from a metal atom to a nonmetal atom, resulting in the formation of cations (positive ions) and anions (negative ions).
Covalent Bonds: Formed when two nonmetals share electrons.
Single bond: One pair of shared electrons.
Double bond: Two pairs of shared electrons.
Triple bond: Three pairs of shared electrons.
Hydrogen Bonds: Weak attractions between partially positive and partially negative ends of molecules, important for the properties of water.
Chemical Notation
Representing Chemical Reactions
Chemical notation is used to represent chemical reactions, showing the transformation of reactants into products.
Reactants: Substances that undergo change, written on the left side of the equation.
Products: Substances formed, written on the right side of the equation.
Arrow (→): Indicates the direction of the reaction.
Energy and Chemical Reactions
Forms of Energy
Energy is the capacity to do work. In biological systems, energy is required for chemical reactions and cellular processes.
Potential Energy: Stored energy due to position or structure.
Kinetic Energy: Energy of motion.
Types of Chemical Reactions
Chemical reactions in the body are essential for metabolism and homeostasis.
Decomposition Reactions: Large substances are broken down into smaller substances.
Synthesis Reactions: Small subunits are combined to make larger, more complex substances.
Exchange Reactions: Atoms are exchanged between reactants.
Water
Properties of Water
Water is vital for life and is the most abundant molecule in the human body. It is a polar molecule, allowing it to dissolve many substances.
Hydrophilic: "Water-loving" substances that dissolve in water.
Hydrophobic: "Water-fearing" substances that do not dissolve in water, such as oils and fats.
Acids and Bases
pH and Buffer Systems
Acids and bases are important for maintaining the body's pH balance. The pH scale measures the concentration of hydrogen ions in a solution.
Acid: Substance that releases hydrogen ions () in solution.
Base: Substance that removes hydrogen ions or releases hydroxide ions ().
pH Scale: Ranges from 0 (most acidic) to 14 (most basic).
Buffer: Chemical system that resists changes in pH.
Monomers and Polymers
Biological Macromolecules
Macromolecules in the body are built from smaller units called monomers. Polymers are chains of monomers linked by chemical bonds.
Hydrolysis: Catabolic reaction that uses water to break up polymers into smaller subunits.
Carbohydrates
Structure and Function
Carbohydrates are organic molecules composed of carbon, hydrogen, and oxygen. They serve primarily as a source of fuel for the body.
Monosaccharides: Simple sugars (e.g., glucose).
Polysaccharides: Complex carbohydrates (e.g., starch, glycogen).
Lipids
Types and Functions
Lipids are a group of nonpolar hydrophobic molecules composed mainly of carbon and hydrogen. They include fats, oils, and steroids.
Fatty Acids: Building blocks of lipids.
Saturated Fats: Solid at room temperature, no double bonds between carbon atoms.
Unsaturated Fats: Liquid at room temperature, have one or more double bonds between carbon atoms.
Proteins
Structure and Roles
Proteins are polymers made of amino acids. They play diverse roles in the body, including structural support, catalysis, and regulation.
Enzymes: Proteins that catalyze chemical reactions.
Building Blocks: Amino acids.
Nucleotides and Nucleic Acids
DNA and RNA Structure
Nucleic acids are polymers of nucleotides and are essential for genetic information storage and transfer.
DNA: Contains the bases adenine (A), guanine (G), cytosine (C), and thymine (T).
RNA: Contains the bases adenine (A), guanine (G), cytosine (C), and uracil (U) (instead of thymine).
Function: DNA stores genetic information; RNA is involved in protein synthesis.
Genetic Information Flow
Transcription: DNA is used as a template to make RNA.
Translation: RNA directs the synthesis of proteins.
Summary Table: Major Elements in the Human Body
Element | Symbol | Function |
|---|---|---|
Oxygen | O | Cellular respiration, water formation |
Carbon | C | Backbone of organic molecules |
Hydrogen | H | Component of water, organic molecules |
Nitrogen | N | Component of proteins and nucleic acids |
Summary Table: Types of Chemical Bonds
Bond Type | Description | Example |
|---|---|---|
Ionic | Transfer of electrons | NaCl (sodium chloride) |
Covalent | Sharing of electrons | H2O (water) |
Hydrogen | Weak attraction between molecules | Between water molecules |
Summary Table: pH Scale
pH Value | Type | Example |
|---|---|---|
0-6 | Acidic | Stomach acid |
7 | Neutral | Pure water |
8-14 | Basic (alkaline) | Blood, bleach |
Additional info: Some explanations and examples have been expanded for clarity and completeness, based on standard Anatomy & Physiology curriculum.