Question 1

Which of the following is NOT considered a physical barrier in the innate immune system?

Accepted Answer

Sebum (acidic mantle of skin)

Question 2

A patient with a genetic defect preventing the production of lysozyme would be most susceptible to infections in which of the following areas?

Accepted Answer

Saliva and tears

Question 3

Which of the following best describes the role of Natural Killer (NK) cells in innate immunity?

Accepted Answer

They perform immune surveillance and destroy abnormal cells.

Question 4

During inflammation, which chemical is primarily responsible for increasing vascular permeability and promoting the migration of immune cells to the site of injury?

Accepted Answer

Histamine

Question 5

Which of the following is a function of the complement system in innate immunity?

Accepted Answer

Opsonization, which enhances phagocytosis of pathogens

Question 6

A child accidentally ingests a large amount of bacteria. Which first line of defense mechanism is most likely to prevent infection in the gastrointestinal tract?

Accepted Answer

Hydrochloric acid (HCl) in the stomach

Question 7

Which of the following statements about fever is correct?

Accepted Answer

Fever accelerates metabolic activity and body defenses.

Question 8

Which antimicrobial protein is produced in response to viral infection and helps protect neighboring cells?

Accepted Answer

Interferon (IFN)

Question 9

A patient with a deficiency in neutrophils would have impaired function in which aspect of innate immunity?

Accepted Answer

Phagocytosis of bacteria

Question 10

Which of the following is an example of a chemical barrier in the first line of defense?

Accepted Answer

Acidity of stomach and vagina

Question 11

Which process involves the movement of phagocytes toward the site of infection in response to chemical signals?

Accepted Answer

Chemotaxis

Question 12

Which of the following is TRUE regarding defensins?

Accepted Answer

They provide a chemical barrier, have direct antimicrobial activity, and support immune functions.

Question 13

Which pathway of complement activation is triggered by antibodies binding to invading organisms?

Accepted Answer

Classical pathway

Question 14

Which of the following is a direct result of increased vascular permeability during inflammation?

Accepted Answer

More immune cells and proteins can enter the affected tissue.

Question 15

Which of the following is NOT a function of the innate immune system?

Accepted Answer

Production of highly specific antibodies

Question 16

A patient with a burn injury loses the integrity of their skin. Which aspect of innate immunity is most compromised?

Accepted Answer

Physical barrier to pathogens

Question 17

Which of the following best explains why mucus in the respiratory tract is important for innate immunity?

Accepted Answer

It traps microbes and particulates, preventing them from reaching deeper tissues.

Question 18

Which of the following is a multi-step process involving recognition, engulfment, and destruction of pathogens by immune cells?

Accepted Answer

Phagocytosis

Question 19

Which of the following is a real-life example of a chemical defense in the innate immune system?

Accepted Answer

The acidic pH of the stomach destroying ingested microbes

Question 20

Which equation best represents the relationship between fever and metabolic rate in the body?

Accepted Answer

$$Metabolic\ Rate \propto Body\ Temperature$$

Innate Immunity: Nonspecific Defense System (Chapter 20)

Guida di studio - Domande di pratica

Study guide - Flashcard