Question 1

Which property of skeletal muscle allows it to respond to a stimulus from the nervous system?

Accepted Answer

Excitability (Irritability)

Question 2

A patient is unable to produce enough heat to maintain body temperature after exposure to cold. Which major function of skeletal muscle is most directly impaired?

Accepted Answer

Produce heat (thermogenesis)

Question 3

Which connective tissue layer surrounds each individual muscle fiber?

Accepted Answer

Endomysium

Question 4

What is the primary role of the sarcoplasmic reticulum in skeletal muscle contraction?

Accepted Answer

Release calcium ions ($$\mathrm{Ca$$^{2+}$$}) $$into the cytoplasm

Question 5

During muscle contraction, which protein forms cross-bridges with actin filaments?

Accepted Answer

Myosin

Question 6

A muscle fiber is stimulated by a motor neuron. Which event occurs first at the neuromuscular junction?

Accepted Answer

Release of acetylcholine (ACh) from the axon terminal

Question 7

Which type of ion channel opens in response to a change in membrane voltage during muscle contraction?

Accepted Answer

Voltage-gated channel

Question 8

A muscle is overstretched before contraction. According to the length-tension relationship, what is the expected effect on force production?

Accepted Answer

Force production decreases due to fewer cross-bridges

Question 9

Which structure is the contractile unit of the muscle fiber?

Accepted Answer

Sarcomere

Question 10

A toxin blocks acetylcholinesterase at the neuromuscular junction. What is the most likely effect on muscle contraction?

Accepted Answer

Muscle contraction will be prolonged due to persistent ACh

Question 11

Which phase of skeletal muscle contraction involves the release of $$\mathrm{Ca$$^{2+}$$}$$ from the sarcoplasmic reticulum?

Accepted Answer

Excitation-contraction coupling phase

Question 12

A muscle fiber is unable to conduct electrical charges. Which property is most directly affected?

Accepted Answer

Conductivity

Question 13

Which of the following best describes a motor unit?

Accepted Answer

A group of muscle fibers innervated by a single motor neuron

Question 14

Which protein blocks the myosin binding sites on actin in a relaxed muscle?

Accepted Answer

Tropomyosin

Question 15

A patient with a genetic defect in titin is likely to have problems with which aspect of muscle function?

Accepted Answer

Elasticity

Question 16

Which event directly triggers the sliding filament mechanism in muscle contraction?

Accepted Answer

Binding of myosin heads to actin

Question 17

Which of the following is NOT a function of skeletal muscle?

Accepted Answer

Synthesis of hormones

Question 18

A muscle fiber is unable to return to its original length after contraction. Which property is most likely impaired?

Accepted Answer

Elasticity

Question 19

Which structure allows the action potential to travel deep into the muscle fiber, ensuring uniform contraction?

Accepted Answer

T-tubules

Question 20

A patient presents with muscle weakness and inability to contract muscles efficiently. Laboratory tests show a deficiency in ATP production. Which distinguishing characteristic of muscle tissue is most directly affected?

Accepted Answer

Ability to transform ATP into directed mechanical energy

Muscle Tissue: Structure, Function, and Physiology

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